Premier Family Care

Archive for August, 2010

The decision of when to perform a laboratory evaluation or a hair analysis test in women experiencing hair loss should be made on an individual basis by the hair restoration specialist. In this article we briefly describe some of the situations where a hair restoration doctor may order lab tests. It is important to note that this is just an overview for your general information so you can understand the reason and the result if you are asked for hair analysis or laboratory tests.

When a hair loss specialist or physician orders some laboratory tests, these hair analysis tests are ordered only after specific clinical information or after observing and carefully evaluating your hair loss. Understanding the basis of these hair analysis tests helps you to understand the cause of your hair loss and also helps you to make an informed decision for a particular hair loss treatment.

While hair loss directly due to a deficiency in a nutrient is believed to be rare, a large industry has developed in recent years based on nutrient “hair analysis”. Several clinics and laboratories claim to be able to define a deficiency of a nutrient or vitamin through analyzing a sample of your hair. The Internet enables these clinics and laboratories to advertise worldwide and a quick search should provide you with numerous web sites offering hair analysis.

These investigations have a simple yes – no question, is the drug, toxin, or heavy metal there or not? There is also the advantage that most of the metals and toxins looked for have a fairly stable chemical nature. They are un-reactive compared to nutrients so they are less likely to change with exposure to the environment. With nutrient analysis the laboratory is attempting to define shades of gray – exactly how much of the nutrient is there? This has been shown to be virtually impossible to do. Even sending hair samples from the same donor to different analysis labs yields contrasting results.
Each vitamin and most minerals are present in blood in extremely small concentrations. Blood also contains a great number of chemicals and molecules and many of these tend to interfere with vitamin and mineral tests. For this reason, a procedure like HPLC (high pressure liquid chromatography) that separates the vitamin or mineral from contaminating substances is usually performed prior to conducting the actual test.

Following separation or purification by HPLC, the vitamin or mineral is detected by a color reaction or fluorescence reaction. In these reactions, the amount of color or fluorescence that is formed is proportional to the amount of vitamin or mineral in the sample, allowing the amount of nutrient present in the original sample to be calculated. In the case of some nutrients, the purified factor of interest is reacted with a special chemical (reagent) prior to detection.

Hair analysis helps the hair loss specialist to reach a diagnosis on hair loss. There can be several Causes of Hair Loss in Women and Hair Loss in Men and after a correct diagnosis is made, the correct women hair restoration treatment can be suggested.
This is not to say all hair analysis is invalid. Analysis of hair is a very useful method of defining exposure to heavy metals. A hair analysis can reveal whether a person has had a chronic exposure to chemical toxins in the environment. And of course hair analysis can be used to show that an individual has been using illegal drugs. The test is known as Hair Follicle Drug Testing. These forms of hair analysis are looking for the presence of a particular chemical that is not normally found in hair, or looking for expression over and above that which is known to be safe.

Garland Valley RN,BSN

Fitness and exercise are gaining popularity in our culture for many reasons. Reactions against the sedentary lifestyles Americans have lived for decades, a rash of type two diabetes with people engaging in fitness and exercise to improve their conditions, parents encouraging youngsters to get up and away from the television and work out, and the baby boomers, pursuing fitness and exercise as they age, to allow them to enjoy their advanced years. Regardless of the reasons, many Americans take fitness and exercise very seriously.

A healthy body is what most people are striving for. We are inundated constantly with images of slender, toned people. Be it on television or on a billboard as we’re driving down the street. Fitness isn’t all about the weight that the scale says or the dress or trouser size you wear. Fitness is about how healthy you are.

Exercise is vital in the quest for body fitness. Many people join a gym for the convenience of having all the equipment they feel they need to work out. There are machines there to strengthen and tone every muscle in your body. With the onset of personal trainers, the process can be almost effortless. In that case, the exerciser is given a prescribed routine of exercise that will help them achieve the fitness level and body weight that they desire.

Fitness and exercise aren’t restricted to the confines of a gym. Any type of movement can be considered exercise. By taking those movements, a step further a person can work towards their own personal fitness goal.

For a person who lives in an apartment building, the decision of whether to take the stairs or the elevator might seem inconsequential, but those steps up to their floor everyday equal a leg workout. Choosing to hike it up the flight of steps gives not only the legs a chance to stretch, but it also gives the heart a chance to beat faster. By choosing this everyday, the body would begin to respond in a positive way.

The same can be said for walking as opposed to driving. Often when a destination is close people feel inclined to get in their car and drive there and then drive the route back. Lacing up a pair of walking shoes and heading out the door on foot is considered exercise and the benefits aren’t only restricted to the gasoline that will be saved. The entire body will feel the results and if that walk is taken several times a week, perhaps even daily, the fitness level of that person increases.

Exercise can occur in almost every environment. It’s up to the health-conscious person to grab those moments and seize them. By mowing the lawn, the legs and arms are being worked out. Carrying the laundry is akin to lifting lightweights and chasing a toddler eventually equals a few laps around the running track. Paying attention to these same details and using them to their fitness advantage will result in so many health benefits.

Non-Hodgkin’s lymphoma is a slow-growing, life-threatening cancer of the immune system that develops when white blood cells grow uncontrollably in the lymph nodes. Each year in the U.S. alone, 55,000 new cases are diagnosed. Fortunately, novel, highly personalized treatments are being produced. With a recent medical breakthrough, patients can now receive individualized treatment that kills cancerous cells while sparing normal, healthy cells.

Traditional treatments usually consist of chemotherapy and monoclonal antibody drugs, which, along with targeting cancerous B-cells, kill healthy white blood cells that comprise a major component of the immune system.

Biovest International is one of a few companies working on patient-specific cancer vaccines. Biovest’s personalized therapeutic, BiovaxID, is currently being tested as a treatment for indolent (slow-growing) follicular B-cell non-Hodgkin’s lymphoma, which affects 12,500 new patients in the U.S. each year. The vaccine could eventually be used to treat other cancers.

Personalizing BiovaxID begins with a sampling of cancerous cells from a patient’s lymph nodes. On the surface of these cells are unique proteins, or antigens, detectable by the immune system. The doctor sends this sample of the patient’s cancer cells to Biovest’s laboratory in Worcester, Mass. Here, researchers mix the cells with another line of cells licensed from Stanford University. The cells fuse, releasing the antigen proteins.

As the patient undergoes chemotherapy to kill most of the cancer cells, Biovest collects and purifies the patient’s antigen proteins, which, after chemical modification, form the active ingredient of the custom vaccine. The individualized vaccine is then sent back to the doctor, who injects it into the patient five times over six months.

“Typical treatments for non-Hodgkin’s do not specifically target the tumor,” explains Dr. Carl M. Cohen, Biovest Chief Operating Officer. “Our vaccine trains the patient’s immune system to target a specific protein on the tumor cells-one found only on the tumor cells. BiovaxID only kills cancer cells. If you think of chemotherapy as a blunt instrument, our treatment is like tweezers.”

Results from a Biovest study of 20 patients, begun at the National Cancer Institute a decade ago, show a 95 percent survival rate. Forty-five percent are still in remission. According to historical data, only about half the patients would have survived with conventional treatments. None would still be in remission. (The Biovest-treated patients remained disease-free for a median of eight years.)

Currently, Biovest is enrolling patients for a large-scale study to be held at several major U.S. and European medical institutions. The trial will include 460 patients. Company officials hope to obtain FDA approval for the vaccine by 2010.